Selected Publications (Most recent first) (Click Here for Pubmed)
21: IH Cho, LC Panzera, M Chin**, SA Alpizar, GE Olveda, RA Hill, MB Hoppa*. The Potassium Channel Subunit Kvβ1 serves as a major control point for synaptic facilitation. PNAS. 2020 Nov 9:202000790. doi: 10.1073/pnas.2000790117.
20: Edwards KA, Hoppa MB, Bosco G*. The Photoconvertible Fluorescent Probe, CaMPARI, Labels Active Neurons in Freely-Moving Intact Adult Fruit Flies. Front. Cell. Neurosci. 2020 May 8;14:22. doi: 10.3389/fncir.2020.00022.
19: Perez-Alvarez A, Schulze C, Fearey BC, Moeyaert B, O’Toole RJ, Mohr MA, Arganda-Carreras I, Yang W, Wiegert JS, Schreiter ER, Gee CE, Hoppa MB, Oertner T*. Freeze-Frame Imaging of Synaptic Activity Using SynTagAM. Nature Communications. 2020 May 18;11(1):2464. doi: 10.1038/s41467-020-16315-4.
18: Panzera LC, Hoppa MB*. Genetically Encoded Voltage Indicators are Illuminating Subcellular Physiology of the Axon. Front. Cell. Neurosci., 01 March 2019| doi: 10.3389/fncel.2019.00052
17: Alpizar SA, Cho IH, Hoppa MB*. Subcellular Control of Membrane Excitability in the Axon. Curr Opin Neurobiol. 2019 Feb 19;57:117-125. doi: 10.1016/j.conb.2019.01.020. PMID: 30784979.
16: Alpizar SA, Baker AL, Gulledge AT, Hoppa MB*. Loss of Neurofascin-186 Disrupts Alignment of AnkyrinG Relative to Its Binding Partners in the Axon Initial Segment. Front Cell Neurosci. 2019 Jan 22;13:1. doi: 10.3389/fncel.2019.00001. PMID: 30723396.
15: Cho IH, Panzera LC, Chin M**, Hoppa MB*. Sodium Channel β2 Subunits Prevent
Action Potential Propagation Failures at Axonal Branch Points. J Neurosci. 2017
Sep 27;37(39):9519-9533.
14: Kyung JW, Cho IH, Lee S, Song WK, Ryan TA, Hoppa MB*, Kim SH*. Adaptor Protein 2 (AP-2) complex is essential for functional axogenesis in hippocampal neurons. Sci Rep. 2017 Jan 31;7:41620. (*Co-corresponding authors)
13: Baumgart JP, Zhou ZY, Hara M, Cook DC, Hoppa MB, Ryan TA, Hemmings HC Jr. Isoflurane inhibits synaptic vesicle exocytosis through reduced Ca2+ influx, not Ca2+-exocytosis coupling. Proc Natl Acad Sci U S A. 2015 Sep 22;112(38):11959-64. doi: 10.1073/pnas.1500525112. Epub 2015 Sep 8. PubMed PMID: 26351670.
12: Hoppa MB, Gouzer G, Armbruster M, Ryan TA. Control and plasticity of the presynaptic action potential waveform at small CNS nerve terminals. Neuron. 2014 Nov 19;84(4):778-89. doi: 10.1016/j.neuron.2014.09.038. Epub 2014 Oct 30. PubMed PMID: 25447742.
11: Ariel P, Hoppa MB, Ryan TA. Intrinsic variability in Pv, RRP size, Ca(2+) channel repertoire, and presynaptic potentiation in individual synaptic boutons. Front Synaptic Neurosci. 2013 Jan 11;4:9. doi: 10.3389/fnsyn.2012.00009. eCollection 2012. PubMed PMID: 23335896.
10: Hoppa MB, Lana B, Margas W, Dolphin AC, Ryan TA. α2δ expression sets presynaptic calcium channel abundance and release probability. Nature. 2012 May 13;486(7401):122-5. doi: 10.1038/nature11033. PubMed PMID: 22678293.
*** Cited Faculty of 1000
9: Hoppa MB, Jones E, Karanauskaite J, Ramracheya R, Braun M, Collins SC, Zhang Q, Clark A, Eliasson L, Genoud C, Macdonald PE, Monteith AG, Barg S, Galvanovskis J, Rorsman P. Multivesicular exocytosis in rat pancreatic beta cells. Diabetologia. 2012 Apr;55(4):1001-12. doi: 10.1007/s00125-011-2400-5. Epub 2011 Dec 22. PubMed PMID: 22189485.
*** Highlighted Article with Preview
8: Collins SC, Hoppa MB, Walker JN, Amisten S, Abdulkader F, Bengtsson M, Fearnside J, Ramracheya R, Toye AA, Zhang Q, Clark A, Gauguier D, Rorsman P. Progression of diet-induced diabetes in C57BL6J mice involves functional dissociation of Ca2(+) channels from secretory vesicles. Diabetes. 2010 May;59(5):1192-201. doi: 10.2337/db09-0791. Epub 2010 Feb 11. PubMed PMID: 20150285.
7: Collins JM, Neville MJ, Hoppa MB, Frayn KN. De novo lipogenesis and stearoyl-CoA desaturase are coordinately regulated in the human adipocyte and protect against palmitate-induced cell injury. J Biol Chem. 2010 Feb 26;285(9):6044-52. doi: 10.1074/jbc.M109.053280. Epub 2009 Dec 23. PubMed PMID: 20032470.
6: Hoppa MB, Collins S, Ramracheya R, Hodson L, Amisten S, Zhang Q, Johnson P, Ashcroft FM, Rorsman P. Chronic palmitate exposure inhibits insulin secretion by dissociation of Ca(2+) channels from secretory granules. Cell Metab. 2009 Dec;10(6):455-65. doi: 10.1016/j.cmet.2009.09.011. PubMed PMID: 19945403;
5: Cnop M, Hughes SJ, Igoillo-Esteve M, Hoppa MB, Sayyed F, van de Laar L, Gunter JH, de Koning EJ, Walls GV, Gray DW, Johnson PR, Hansen BC, Morris JF, Pipeleers-Marichal M, Cnop I, Clark A. The long lifespan and low turnover of human islet beta cells estimated by mathematical modelling of lipofuscin accumulation. Diabetologia. 2010 Feb;53(2):321-30. doi: 10.1007/s00125-009-1562-x. Epub 2009 Oct 24. PubMed PMID: 19855953.
4: Li DQ, Jing X, Salehi A, Collins SC, Hoppa MB, Rosengren AH, Zhang E, Lundquist I, Olofsson CS, Mörgelin M, Eliasson L, Rorsman P, Renström E. Suppression of sulfonylurea- and glucose-induced insulin secretion in vitro and in vivo in mice lacking the chloride transport protein ClC-3. Cell Metab. 2009 Oct;10(4):309-15. doi: 10.1016/j.cmet.2009.08.011. PubMed PMID: 19808023.
3: Pigeau GM, Kolic J, Ball BJ, Hoppa MB, Wang YW, Rückle T, Woo M, Manning Fox JE, MacDonald PE. Insulin granule recruitment and exocytosis is dependent on p110gamma in insulinoma and human beta-cells. Diabetes. 2009 Sep;58(9):2084-92. doi: 10.2337/db08-1371. Epub 2009 Jun 23. PubMed PMID: 19549714.
2: Karanauskaite J, Hoppa MB, Braun M, Galvanovskis J, Rorsman P. Quantal ATP release in rat beta-cells by exocytosis of insulin-containing LDCVs. Pflugers Arch. 2009 Jun;458(2):389-401. doi: 10.1007/s00424-008-0610-6. Epub 2008 Nov 19. PubMed PMID: 19018564.
1: Eliasson L, Abdulkader F, Braun M, Galvanovskis J, Hoppa MB, Rorsman P. Novel aspects of the molecular mechanisms controlling insulin secretion. J Physiol. 2008 Jul 15;586(14):3313-24. doi: 10.1113/jphysiol.2008.155317. Epub 2008 May 29. Review. PubMed PMID: 18511483.
21: IH Cho, LC Panzera, M Chin**, SA Alpizar, GE Olveda, RA Hill, MB Hoppa*. The Potassium Channel Subunit Kvβ1 serves as a major control point for synaptic facilitation. PNAS. 2020 Nov 9:202000790. doi: 10.1073/pnas.2000790117.
20: Edwards KA, Hoppa MB, Bosco G*. The Photoconvertible Fluorescent Probe, CaMPARI, Labels Active Neurons in Freely-Moving Intact Adult Fruit Flies. Front. Cell. Neurosci. 2020 May 8;14:22. doi: 10.3389/fncir.2020.00022.
19: Perez-Alvarez A, Schulze C, Fearey BC, Moeyaert B, O’Toole RJ, Mohr MA, Arganda-Carreras I, Yang W, Wiegert JS, Schreiter ER, Gee CE, Hoppa MB, Oertner T*. Freeze-Frame Imaging of Synaptic Activity Using SynTagAM. Nature Communications. 2020 May 18;11(1):2464. doi: 10.1038/s41467-020-16315-4.
18: Panzera LC, Hoppa MB*. Genetically Encoded Voltage Indicators are Illuminating Subcellular Physiology of the Axon. Front. Cell. Neurosci., 01 March 2019| doi: 10.3389/fncel.2019.00052
17: Alpizar SA, Cho IH, Hoppa MB*. Subcellular Control of Membrane Excitability in the Axon. Curr Opin Neurobiol. 2019 Feb 19;57:117-125. doi: 10.1016/j.conb.2019.01.020. PMID: 30784979.
16: Alpizar SA, Baker AL, Gulledge AT, Hoppa MB*. Loss of Neurofascin-186 Disrupts Alignment of AnkyrinG Relative to Its Binding Partners in the Axon Initial Segment. Front Cell Neurosci. 2019 Jan 22;13:1. doi: 10.3389/fncel.2019.00001. PMID: 30723396.
15: Cho IH, Panzera LC, Chin M**, Hoppa MB*. Sodium Channel β2 Subunits Prevent
Action Potential Propagation Failures at Axonal Branch Points. J Neurosci. 2017
Sep 27;37(39):9519-9533.
14: Kyung JW, Cho IH, Lee S, Song WK, Ryan TA, Hoppa MB*, Kim SH*. Adaptor Protein 2 (AP-2) complex is essential for functional axogenesis in hippocampal neurons. Sci Rep. 2017 Jan 31;7:41620. (*Co-corresponding authors)
13: Baumgart JP, Zhou ZY, Hara M, Cook DC, Hoppa MB, Ryan TA, Hemmings HC Jr. Isoflurane inhibits synaptic vesicle exocytosis through reduced Ca2+ influx, not Ca2+-exocytosis coupling. Proc Natl Acad Sci U S A. 2015 Sep 22;112(38):11959-64. doi: 10.1073/pnas.1500525112. Epub 2015 Sep 8. PubMed PMID: 26351670.
12: Hoppa MB, Gouzer G, Armbruster M, Ryan TA. Control and plasticity of the presynaptic action potential waveform at small CNS nerve terminals. Neuron. 2014 Nov 19;84(4):778-89. doi: 10.1016/j.neuron.2014.09.038. Epub 2014 Oct 30. PubMed PMID: 25447742.
11: Ariel P, Hoppa MB, Ryan TA. Intrinsic variability in Pv, RRP size, Ca(2+) channel repertoire, and presynaptic potentiation in individual synaptic boutons. Front Synaptic Neurosci. 2013 Jan 11;4:9. doi: 10.3389/fnsyn.2012.00009. eCollection 2012. PubMed PMID: 23335896.
10: Hoppa MB, Lana B, Margas W, Dolphin AC, Ryan TA. α2δ expression sets presynaptic calcium channel abundance and release probability. Nature. 2012 May 13;486(7401):122-5. doi: 10.1038/nature11033. PubMed PMID: 22678293.
*** Cited Faculty of 1000
9: Hoppa MB, Jones E, Karanauskaite J, Ramracheya R, Braun M, Collins SC, Zhang Q, Clark A, Eliasson L, Genoud C, Macdonald PE, Monteith AG, Barg S, Galvanovskis J, Rorsman P. Multivesicular exocytosis in rat pancreatic beta cells. Diabetologia. 2012 Apr;55(4):1001-12. doi: 10.1007/s00125-011-2400-5. Epub 2011 Dec 22. PubMed PMID: 22189485.
*** Highlighted Article with Preview
8: Collins SC, Hoppa MB, Walker JN, Amisten S, Abdulkader F, Bengtsson M, Fearnside J, Ramracheya R, Toye AA, Zhang Q, Clark A, Gauguier D, Rorsman P. Progression of diet-induced diabetes in C57BL6J mice involves functional dissociation of Ca2(+) channels from secretory vesicles. Diabetes. 2010 May;59(5):1192-201. doi: 10.2337/db09-0791. Epub 2010 Feb 11. PubMed PMID: 20150285.
7: Collins JM, Neville MJ, Hoppa MB, Frayn KN. De novo lipogenesis and stearoyl-CoA desaturase are coordinately regulated in the human adipocyte and protect against palmitate-induced cell injury. J Biol Chem. 2010 Feb 26;285(9):6044-52. doi: 10.1074/jbc.M109.053280. Epub 2009 Dec 23. PubMed PMID: 20032470.
6: Hoppa MB, Collins S, Ramracheya R, Hodson L, Amisten S, Zhang Q, Johnson P, Ashcroft FM, Rorsman P. Chronic palmitate exposure inhibits insulin secretion by dissociation of Ca(2+) channels from secretory granules. Cell Metab. 2009 Dec;10(6):455-65. doi: 10.1016/j.cmet.2009.09.011. PubMed PMID: 19945403;
5: Cnop M, Hughes SJ, Igoillo-Esteve M, Hoppa MB, Sayyed F, van de Laar L, Gunter JH, de Koning EJ, Walls GV, Gray DW, Johnson PR, Hansen BC, Morris JF, Pipeleers-Marichal M, Cnop I, Clark A. The long lifespan and low turnover of human islet beta cells estimated by mathematical modelling of lipofuscin accumulation. Diabetologia. 2010 Feb;53(2):321-30. doi: 10.1007/s00125-009-1562-x. Epub 2009 Oct 24. PubMed PMID: 19855953.
4: Li DQ, Jing X, Salehi A, Collins SC, Hoppa MB, Rosengren AH, Zhang E, Lundquist I, Olofsson CS, Mörgelin M, Eliasson L, Rorsman P, Renström E. Suppression of sulfonylurea- and glucose-induced insulin secretion in vitro and in vivo in mice lacking the chloride transport protein ClC-3. Cell Metab. 2009 Oct;10(4):309-15. doi: 10.1016/j.cmet.2009.08.011. PubMed PMID: 19808023.
3: Pigeau GM, Kolic J, Ball BJ, Hoppa MB, Wang YW, Rückle T, Woo M, Manning Fox JE, MacDonald PE. Insulin granule recruitment and exocytosis is dependent on p110gamma in insulinoma and human beta-cells. Diabetes. 2009 Sep;58(9):2084-92. doi: 10.2337/db08-1371. Epub 2009 Jun 23. PubMed PMID: 19549714.
2: Karanauskaite J, Hoppa MB, Braun M, Galvanovskis J, Rorsman P. Quantal ATP release in rat beta-cells by exocytosis of insulin-containing LDCVs. Pflugers Arch. 2009 Jun;458(2):389-401. doi: 10.1007/s00424-008-0610-6. Epub 2008 Nov 19. PubMed PMID: 19018564.
1: Eliasson L, Abdulkader F, Braun M, Galvanovskis J, Hoppa MB, Rorsman P. Novel aspects of the molecular mechanisms controlling insulin secretion. J Physiol. 2008 Jul 15;586(14):3313-24. doi: 10.1113/jphysiol.2008.155317. Epub 2008 May 29. Review. PubMed PMID: 18511483.